Acetaminophen and Xenobiotic Metabolites in Human Milk and the Development of Bronchopulmonary Dysplasia and Retinopathy of Prematurity in a Cohort of Extremely Preterm Infants

Breast milk is a complex matrix of bioactive components that provides health benefits for newborns.(1, 2) Preterm infants that are fed maternal breast milk versus formula experience less necrotizing enterocolitis (NEC) (3, 4), retinopathy of prematurity (ROP) (5, 6), and improved neurodevelopmental outcomes (7). Despite this, challenges remain in thoroughly accounting for all the effects that breast milk can have on newborn health due to the large variability in breast milk composition and difficulties in the past with the sampling of breast milk and analysis of metabolites.

source https://www.jpeds.com/article/S0022-3476(22)00056-7/fulltext?rss=yes

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