Neonatal Hypotonia Following in Utero Exposure to Antidepressant Drugs

Associations between fetal exposure to antidepressants and neonatal hypotonia were studied using VigiBase® and the French PharmacoVigilance Database. We identified significant associations between neonatal hypotonia and clomipramine, venlafaxine, and imipramine. Reports from the French database implicated prolonged fetal exposure. Neonatal hypotonia may be associated with in utero exposure to antidepressants.

source https://www.jpeds.com/article/S0022-3476(22)00149-4/fulltext?rss=yes

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