Vesiculopustular rash in a neonate

A 7-day-old girl, born at term following an uncomplicated pregnancy and delivery, presented to the dermatology clinic for evaluation of a blistering rash present since birth. Examination revealed numerous erythematous vesicles and pustules, some with associated crusting, arranged in a Blaschkolinear pattern across all four extremities (Figures 1-3). Review of systems was negative for fever, lethargy, irritability, or seizure-like activity. Although a diagnosis of incontinentia pigmenti (IP) wassuspected, she was admitted for empiric antiviral treatment and comprehensive infectious workup given the potential significance of an untreated neonatal infection.

source https://www.jpeds.com/article/S0022-3476(22)00210-4/fulltext?rss=yes

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