Trametinib for refractory chylous effusions and systemic complications in children with Noonan syndrome

To evaluate the effect of RAS-MAPK pathway inhibitor Trametinib on medically refractory chylous effusions in three hospitalized patients with Noonan syndrome.

source https://www.jpeds.com/article/S0022-3476(22)00479-6/fulltext?rss=yes

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