Bilateral Marcus Gunn Jaw-Winking Syndrome in a Neonate with Congenital Neurosyphilis

A 4-week-old male born at 33-week gestation presented with repetitive bilateral eyelid blinking with feeds. The pregnancy was complicated by maternal syphilis and methamphetamine exposure. Prenatal laboratory tests on admission showed maternal rapid plasma reagin (RPR) positivity (1:64), and the baby was subsequently found to have a positive serum RPR (1:4) and positive venereal disease research laboratory (VDRL) in cerebrospinal fluid (1:1). The baby's urine toxicology screen was negative. The general examination demonstrated hepatomegaly and syphilitic rhinitis (snuffles); there were otherwise no ocular, bone, audiologic, dermatologic, or dental abnormalities.

source https://www.jpeds.com/article/S0022-3476(22)00845-9/fulltext?rss=yes