Febrile preterm infants: they are not just small febrile, term infants

Annually, more than 200,000 febrile infants younger than 90 days are evaluated in U.S. emergency departments (EDs)1 and other outpatient settings. Although urinary tract infections (UTIs) are common in these infants, the main concerns involve invasive bacterial infections (IBI), defined by bacteremia or bacterial meningitis. The reported IBI rates range from approximately 1 to 5% in prospective studies, with higher rates in the youngest infants.2-4 To address the persistent variability in care of these febrile infants despite substantial research performed over several decades, the American Academy of Pediatrics (AAP) published guidelines for the management of well-appearing febrile infants 8-60 days old.

source https://www.jpeds.com/article/S0022-3476(22)00848-4/fulltext?rss=yes