Lack of age-appropriate reference intervals causing potentially missed alerts in clinical reports of dyslipidemia

This study shows that only 12.5% (2/16) laboratory reports included age-appropriate pediatric reference ranges for all lipid/lipoproteins. Use of erroneous reference range(s) could lead to missed alerts of dyslipidemia in up to 97.3% (TC), 93.6% (HDL-C), 94.8% (LDL-C) and 87.8% (TG) of youth in the population based NHANES-cohort. The findings highlight the potential missed opportunities for reinforcing lifestyle counseling for dyslipidemia in addition to obesity in youth.

source https://www.jpeds.com/article/S0022-3476(22)00726-0/fulltext?rss=yes

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