Effect of standing IV acetaminophen on post-operative opioid exposure in a pediatric cardiac ICU

This study assessed the association between standing intravenous acetaminophen and opioid exposure after cardiac surgery. Before versus after implementation of a standardized pain pathway, we report decreased opioid exposure, 0.38 MME/kg [IQR 0.10-0.81] vs. 0.26 MME/kg [0.09-0.56] (p=0.01) and increased acetaminophen exposure, 3 [2-4] vs. 4 [4-5] doses (p<0.001).

source https://www.jpeds.com/article/S0022-3476(22)01112-X/fulltext?rss=yes

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