Splenomegaly in Kawasaki Disease: A Pitfall in Diagnosis

Among 365 children diagnosed as having Kawasaki disease (KD), only five children (1.4%) presented with splenomegaly: two complicated by macrophage activation syndrome (MAS) and three ultimately received a diagnosis of alternative systemic illness. Splenomegaly is atypical in KD and a potential marker of an underling complication, namely MAS, or diagnosis other than KD.

source https://www.jpeds.com/article/S0022-3476(23)00118-X/fulltext?rss=yes

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