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Active treatment of infants born at 22-25 weeks of gestation in California, 2011-2018

To determine the rate and trend of active treatment in a population-based cohort of 22-25 weeks’ gestation infants and to examine factors associated with active treatment. source https://www.jpeds.com/article/S0022-3476(22)00546-7/fulltext?rss=yes

Organizational risk factors and clinical impacts of unplanned extubation in the NICU

To assess the association between organizational factors and unplanned extubation events in the neonatal intensive care unit (NICU) and to evaluate the association between UPE and bronchopulmonary dysplasia (BPD) among infants born <29 weeks gestational age (GA). source https://www.jpeds.com/article/S0022-3476(22)00545-5/fulltext?rss=yes

SIDS: Mystery Solved?

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  Roughly 3,400 infants under 1 year of age die suddenly and unexpectedly — mostly while they sleep — in the United States each year. According to the Centers for Disease Control and Prevention, these sudden unexpected infant deaths (SUID) are understood to be due to three factors: 1. Sudden infant death syndrome (SIDS) 2. Accidental suffocation in a sleep environment 3. Unknown causes   The PediaBlog highlighted effective prevention tactics back in 2015: In 1992, researchers recognized that sudden infant death syndrome (SIDS) could be prevented simply by positioning babies to sleep on their backs rather than their sides or stomachs. Since then, the AAP’s “Back to Sleep” campaign has resulted in a dramatic decrease in SIDS deaths. Eliminating soft bedding and ensuring a safe sleep environment drives that number down further, but not completely. Clearly, there are other factors involved for other SIDS victims, and researchers are narrowing them down. ...

Comparing Serum Matrix Metalloproteinase-7 in Parenteral Nutrition-Associated Liver Disease and Biliary Atresia

In this cross-sectional study. Serum matrix metalloproteinase-7 (MMP-7) levels were significantly lower in jaundiced infants with parenteral nutrition-associated liver disease compared with those with confirmed biliary atresiaSerum MMP-7 may aid in excluding biliary atresia, and thus may minimize invasive testing in infants with a history of parenteral nutrition. source https://www.jpeds.com/article/S0022-3476(22)00547-9/fulltext?rss=yes

Addressing weight stigma and obesity based discrimination in children: preparing pediatricians to meet the challenge

Overweight and obesity affects more than 17% of children worldwide. In the European region, one in three children between the ages of 6 and 9 is currently overweight or obese2, while in the United States, childhood obesity rates have tripled over the past three decades and currently about one in three children is overweight or obese3. The prevalence of obesity in the population aged 2 to 19 years residing in the United States during 2017-2020 was 19.7%, affecting about 14.7 million children and adolescents4. source https://www.jpeds.com/article/S0022-3476(22)00544-3/fulltext?rss=yes

IMPROVING CHOLESTEROL SCREENING IN CHILDREN – IS EDUCATING PRIMARY CARE PROVIDERS ENOUGH?

In this volume of The Journal, Soukup et al1 published their assessment of cholesterol screening practices among pediatric primary care providers (PCPs) and explored barriers and facilitators to successful implementation. It should be noted that recommendations for cholesterol screening are not new. As early as 1992, the U.S. National Cholesterol Education Program (NCEP) advocated cholesterol screening2; and by 1998, the World Health Organization (WHO) recognized hypercholesterolemia as a worldwide public health priority. source https://www.jpeds.com/article/S0022-3476(22)00539-X/fulltext?rss=yes

Longitudinal natural history of pediatric subjects affected with mucopolysaccharidosis IIIB

To characterize the longitudinal natural history of disease progression in pediatric subjects affected with mucopolysaccharidosis IIIB (MPS IIIB). source https://www.jpeds.com/article/S0022-3476(22)00538-8/fulltext?rss=yes